Description:

Retrieve annotation for all the proteins of a given genome that are in the same MCL cluster as the protein with an Enzyme annotation of interest. If no genome is provided, all proteins in the corresponding clusters are retrieved. This can increase the response time of the query considerably, please be patient.

Runtime:

Can take about 1-2 minutes to retrieve proteins of a given genome that are in the same cluster as proteins with a given enzyme annotation.

Input:

Details

Genome	Name of the genome of interest; to retrieve a list of genomes from the database, the button "Existing Values..." can be used.
Enzyme annotation	EC number (without EC) or name of the Enzyme annotation of interest. Using the "Existing values..." feature provides a list of Enzyme annotations to chose from.

Examples

Genome	Enzyme annotation
Trichoderma reesei	3.6.3.1
Saccharomyces cerevisiae	tRNase Z
Ustilago maydis	tryptophan synthase

Output:

Description

Annotation for all proteins (of a given genome) in MCL clusters containing proteins with the Enzyme annotation of interest. Annotation returned includes GO and Enzyme annotation, KEGG pathways the proteins are known to be involved in, identified Pfam motifs, results of Wolf-PSort, PSort and SignalP predictions.

Details

Protein ID	Identifier of the protein.
Symbol	Symbol of the protein.
Genome	Genome that the protein belongs to.
Gene ID	Identifier of the gene.
Locus Tag	Locus Tag of the gene.
Chr	Chromosome on which the gene is located.
Start	Start position of the gene (in bp).
MCL cluster ID	Identifier of the MCL cluster in which the protein can be found.
OrthoMCL cluster ID	Identifier of the OrthoMCL cluster in which the protein can be found.
PSort Prediction	Sub-cellular localisation of the protein as predicted by PSort.
Wolf-PSort Prediction	Sub-cellular localisation of the protein as predicted by Wolf-PSort.
SignalP Prediction	Information whether the protein has been predicted to be a secretory or non-secretory protein (prediction done using SignalP).
GO Annotations	List of all the GO annotations assigned to the protein.
Pfam A Annotations	List of all the Pfam A domains that have been identified for the protein.
Enzymes	List of all the Enzyme annotations assigned to the protein.
Pathways	List of all the KEGG pathways which the protein is part of.
Protein Sequence	Sequence of the protein.