Professor Andy Brass

Andy Brass


I'm a Professor in the Biohealth Informatics Group of the School of Computer Science at the University of Manchester.

Research interests: Bioinformatics, Functional Genomics, Computational Biology


1: Noyes HA, Agaba M, Anderson S, Archibald AL, Brass A, Gibson J, Hall L, Hulme H, Oh SJ, Kemp SJ. Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background. BMC Genomics. 2010 Jun 7;11(1):361. [Epub ahead of print] PubMed PMID: 20529291.

2: Li W, Gracey AY, Mello LV, Brass A, Cossins AR. ExprAlign--the identification of ESTs in non-model species by alignment of cDNA microarray expression profiles. BMC Genomics. 2009 Nov 26;10:560. PubMed PMID: 19939286; PubMed Central PMCID: PMC2790474.

3: Alttoa A, Kõiv K, Hinsley TA, Brass A, Harro J. Differential gene expression in a rat model of depression based on persistent differences in exploratory activity. Eur Neuropsychopharmacol. 2010 May;20(5):288-300. Epub 2009 Oct 24. PubMed PMID: 19854624.

4: Fisher P, Noyes H, Kemp S, Stevens R, Brass A. A systematic strategy for the discovery of candidate genes responsible for phenotypic variation. Methods Mol Biol. 2009;573:329-45. Review. PubMed PMID: 19763936.

5: Rathkolb B, Noyes HA, Brass A, Dark P, Fuchs H, Gailus-Durner V, Gibson J, de Angelis MH, Ogugo M, Iraqi F, Kemp SJ, Naessens J, Pope ME, Wolf E, Agaba M. Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection. Infect Immun. 2009 Sep;77(9):3948-57. Epub 2009 Jul 13. PubMed PMID: 19596769; PubMed Central PMCID: PMC2738039.

6: Morris DG, Waters SM, McCarthy SD, Patton J, Earley B, Fitzpatrick R, Murphy JJ, Diskin MG, Kenny DA, Brass A, Wathes DC. Pleiotropic effects of negative energy balance in the postpartum dairy cow on splenic gene expression: repercussions for innate and adaptive immunity. Physiol Genomics. 2009 Sep 9;39(1):28-37. Epub 2009 Jun 30. PubMed PMID: 19567785; PubMed Central PMCID: PMC2747343.

7: Noyes HA, Alimohammadian MH, Agaba M, Brass A, Fuchs H, Gailus-Durner V, Hulme H, Iraqi F, Kemp S, Rathkolb B, Wolf E, de Angelis MH, Roshandel D, Naessens J. Mechanisms controlling anaemia in Trypanosoma congolense infected mice. PLoS One. 2009;4(4):e5170. Epub 2009 Apr 13. PubMed PMID: 19365556; PubMed Central PMCID: PMC2664899.

8: Rennie C, Hulme H, Fisher P, Halp L, Agaba M, Noyes HA, Kemp SJ, Brass A. A systematic, data-driven approach to the combined analysis of microarray and QTL data. Dev Biol (Basel). 2008;132:293-9. PubMed PMID: 18817316.

9: Rennie C, Noyes HA, Kemp SJ, Hulme H, Brass A, Hoyle DC. Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays. BMC Genomics. 2008 Jul 3;9:317. PubMed PMID: 18598341; PubMed Central PMCID: PMC2475537.

10: Fisher P, Hedeler C, Wolstencroft K, Hulme H, Noyes H, Kemp S, Stevens R, Brass A. A systematic strategy for large-scale analysis of genotype phenotype correlations: identification of candidate genes involved in African trypanosomiasis. Nucleic Acids Res. 2007;35(16):5625-33. Epub 2007 Aug 20. PubMed PMID: 17709344; PubMed Central PMCID: PMC2018629. <\p>

11: Kierstein S, Noyes H, Naessens J, Nakamura Y, Pritchard C, Gibson J, Kemp S, Brass A. Gene expression profiling in a mouse model for African trypanosomiasis. Genes Immun. 2006 Dec;7(8):667-79. Epub 2006 Oct 26. PubMed PMID: 17066074; PubMed Central PMCID: PMC1991335.

12: Morrison N, Wood AJ, Hancock D, Shah S, Hakes L, Gray T, Tiwari B, Kille P, Cossins A, Hegarty M, Allen MJ, Wilson WH, Olive P, Last K, Kramer C, Bailhache T, Reeves J, Pallett D, Warne J, Nashar K, Parkinson H, Sansone SA, Rocca-Serra P, Stevens R, Snape J, Brass A, Field D. Annotation of environmental OMICS data: application to the transcriptomics domain. OMICS. 2006 Summer;10(2):172-8. Review. PubMed PMID: 16901223.

13: Wolstencroft K, Lord P, Tabernero L, Brass A, Stevens R. Protein classification using ontology classification. Bioinformatics. 2006 Jul 15;22(14):e530-8. PubMed PMID: 16873517.

14: Fraser J, de Mello LV, Ward D, Rees HH, Williams DR, Fang Y, Brass A, Gracey AY, Cossins AR. Hypoxia-inducible myoglobin expression in nonmuscle tissues. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2977-81. Epub 2006 Feb 9. Erratum in: Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9374. Fang, Yongchang [corrected to Fang, Yongxiang]. PubMed PMID: 16469844; PubMed Central PMCID: PMC1413783.

15: Hancock D, Wilson M, Velarde G, Morrison N, Hayes A, Hulme H, Wood AJ, Nashar K, Kell DB, Brass A. maxdLoad2 and maxdBrowse: standards-compliant tools for microarray experimental annotation, data management and dissemination. BMC Bioinformatics. 2005 Nov 3;6:264. PubMed PMID: 16269077; PubMed Central PMCID: PMC1298287.

16: Bishop R, Shah T, Pelle R, Hoyle D, Pearson T, Haines L, Brass A, Hulme H, Graham SP, Taracha EL, Kanga S, Lu C, Hass B, Wortman J, White O, Gardner MJ, Nene V, de Villiers EP. Analysis of the transcriptome of the protozoan Theileria parva using MPSS reveals that the majority of genes are transcriptionally active in the schizont stage. Nucleic Acids Res. 2005 Sep 25;33(17):5503-11. Print 2005. PubMed PMID: 16186131; PubMed Central PMCID: PMC1236717.

17: Datta R, deSchoolmeester ML, Hedeler C, Paton NW, Brass AM, Else KJ. Identification of novel genes in intestinal tissue that are regulated after infection with an intestinal nematode parasite. Infect Immun. 2005 Jul;73(7):4025-33. PubMed PMID: 15972490; PubMed Central PMCID: PMC1168561.

18: Wolstencroft K, McEntire R, Stevens R, Tabernero L, Brass A. Constructing ontology-driven protein family databases. Bioinformatics. 2005 Apr 15;21(8):1685-92. Epub 2004 Nov 25. PubMed PMID: 15564301.


Mail: Andy Brass
2.87 Kilburn Building
Oxford Road
M13 9PL
Voice: +44 (0) 161 275 5096