Case Studies for the RASH Process

Three main case studies have been chosen to ellucidate and demonstrate the RASH process:

  1. The development of schema for the SWISS-PROT and PIR protein sequence databanks and their reconciliation to each other and a unifying schema.
  2. The development of schema for each of the Saccharomyces Genome Database (SGD), MIPS Yeast Genome Database (MYDG) and the Yeast Proteome Database (YPD) and their reconciliation to the GIMS (Genome Information Management System) as a unifying schema. GIMS has an object database schema and takes information from each of the yeast databases, so portions of each resource's schema are reconciled with the GIMS schema.
  3. The reconciliation of a variety of schema fragments from several resources, including those above. this would include the concept of gene, function, and other sequence features.

Each of these case studies highlights some commonly occuring features of the reconciliation task in bioinformatics: